Putting the eco in ecotoxicology

Ecotoxicology.

Ethics in science: ecotoxicology

Predictive ecotoxicology emphasizes the probable environmental outcome of exposure to toxics, rather than the mere appraisal of existing damage, and in so doing raises some complex but interesting ethical issues. Awareness of endocrine-disrupting chemicals is blurring the line between humankind and other life forms in toxicity testing by providing evidence that both humans and wildlife suffer a...

Transcriptomics in ecotoxicology

The emergence of analytical tools for high-throughput screening of biomolecules has revolutionized the way in which toxicologists explore the impact of chemicals or other stressors on organisms. One of the most developed and routinely applied high-throughput analysis approaches is transcriptomics, also often referred to as gene expression profiling. The transcriptome represents all RNA molecule...

Nondestructive biomarkers in ecotoxicology.

The aim of this article is to attempt a concise review of the state of the art of the nondestructive biomarkers approach in vertebrates, establishing a consensus on the most useful and sensitive nondestructive biomarker techniques, and proposing research priorities for the development and validation of this promising methodology. The following topics are discussed: the advantages of the use of ...

The use of cholinesterases in ecotoxicology.

Cholinesterase (ChE) is one of the most employed biomakers in environmental analysis. Among ChEs, potentially the most significant in environmental terms is acetylcholinesterase (AChE), an enzymatic form that terminates the nerve impulse . Because of its physiological role, Ache has long been considered a highly specific biomarker for organisms exposed to anticholinesterasic agents, primarily a...